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Endometrial receptivity is the state in which the endometrium is ready for embryonic implantation to take place. This occurs in all menstrual cycles in fertile women at around day 21 of the cycle. Currently, the only study done on the endometrium is an ultrasound scan, and there is no analysis method available that helps doctors in their clinical practice.
Within the study of an infertile couple, the ERA test (Endometrial Receptivity Analysis) assesses the woman’s endometrial receptivity status from the molecular viewpoint as an important analysis of the uterine factor. This molecular tool allows us to diagnose whether the endometrium is receptive or not by analyzing the expression of a group of genes responsible for this function. To go about this, an endometrial biopsy must be done on day 21 of the menstrual cycle (the receptive phase) or on day LH+7, or after 5 days of progesterone in a substitute cycle.