SAT
Sperm aneuploidy test

Analysis of sperm chromosomal abnormalities

Order Now
Scroll Down
 

Overview

  • SAT is a diagnostic test to study the genetic etiology of male infertility.
  • It allows us to evaluate the presence of an abnormal number of chromosomes in the sperm.
  • In couples with severe male factor infertility, there is a higher risk of transmission of sperm chromosomal abnormalities to the offspring.

More Info

Overview

Benefits

  • Increases pregnancy rate.
  • Decreases miscarriage risk.
  • Identify males with low reproductive success chance.
  • Useful tool to provide personalized genetic counseling to the infertile couple previous to an IVF treatment.

In couples with an abnormal SAT, it is indicated to perform PGS (Preimplantation Genetic Screening) to select chromosomally normal embryos for transfer.*
*Rodrigo et al., 2014.

Indications

  • Male factor infertility: low sperm concentration is correlated with a higher incidence of S.C.A.
  • Recurrent miscarriage of unknown etiology.
  • Repetitive implantation failure.
  • Previous pregnancy with a chromosomal abnormality.
Indications

Methodology

Main steps of the assay

Results

An increase of sperm chromosomal abnormalities affects reproduction on 3 levels:

EMBRYO LEVEL

  • Spermatozoa with sex chromosome abnormalities result in aneuploid embryos.
  • Diploid sperm results in triploid embryos.

(Rodrigo et al., 2010)

PREGNANCY LEVEL

  • An elevated SAT decreases pregnancy rates after ICSI.
  • And increases miscarriage rate.

(Rubio et al., 2001)

OFFSPRING LEVEL

  • It increases the risk of abnormal offspring for the chromosomes detected in the sperm (Down, Klinefelter or Turner's Sindromes)

Become our provider

Contact us now and we will guide you through the entire process

CONTACT US

Igenomix is in the media

Igenomix is not affiliated with any news outlet or publication identified above. News coverage does not constitute an endorsement of Igenomix or its products.