Maximize the chances of pregnancy without losing valuable embryos
Launched in 2011, ERA was the first test of its kind, revolutionizing endometrial diagnostics and laying the foundation for personalized fertility treatment. By identifying a woman’s unique window of implantation, it enables precise embryo transfer timing to optimize IVF success. Backed by robust clinical evidence, ERA remains the most advanced and trusted endometrial receptivity test available.
ERA is a proven solution for patients with RIF, powered by the most scientific publications and the highest clinical success rates compared to any other endometrial receptivity test in the market. In fact, ERA is the only endometrial receptivity test backed by an RCT*. This RCT, involving 320 patients with RIF, demonstrated significantly improved reproductive outcomes—including nearly double the live birth rates—for patients who used ERA in combination with PGT-A, compared to those who used PGT-A alone.
Powered by AI, the ERA algorithm is not only based upon the endometrial biopsy data from over 200,000 women but integrates clinical outcomes from personalized embryo transfers guided by its results. Combining this with the most comprehensive gene panel available (248 genes), ERA delivers the most precise transcriptomic profiling and personalized embryo transfer timing—maximizing implantation success.
Backed by a global team of endometrial experts, ERA is the trusted endometrial receptivity test used by over 3,000 clinics worldwide. Our comprehensive support network includes world-class scientific advisors, dedicated endometrial specialists, genetic counsellors, and in-house clinicians—providing expert guidance to clinics and patients every step of the way.
* 2024 Barbakadze et al. Cureus 16(6): e62949. DOI 10.7759/cureus.62949
ERA® test is indicated for patients with recurrent implantation failure.
90 % of cases don’t need a second biopsy. The second biopsy is only required under two circumstances:
Visit the ERA insight Hub – International to download the complete ERA Publication List and explore all related studies.
A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature.
Díaz-Gimeno P, Horcajadas JA, Martínez-Conejero JA, Esteban FJ, Alamá P, Pellicer A, Simón C.
Fertil Steril. 2011 Jan;95(1):50-60, 60.e1-15. doi: 10.1016/j.fertnstert.2010.04.063. Epub 2010 Jul 8.
PMID:20619403
Díaz-Gimeno P, Ruiz-Alonso M, Blesa D, Bosch N, Martínez-Conejero JA, Alamá P, Garrido N, Pellicer A, Simón C.
Fertil Steril. 2013 Feb;99(2):508-17. doi: 10.1016/j.fertnstert.2012.09.046. Epub 2012 Oct 23.
PMID:23102856
Ruiz-Alonso M, Blesa D, Díaz-Gimeno P, Gómez E, Fernández-Sánchez M, Carranza F, Carrera J, Vilella F, Pellicer A, Simón C.
Fertil Steril. 2013 Sep;100(3):818-24. doi: 10.1016/j.fertnstert.2013.05.004. Epub 2013 Jun 4.
PMID:23756099
Ruiz-Alonso M, Blesa D, Díaz-Gimeno P, Gómez E, Fernández-Sánchez M, Carranza F, Carrera J, Vilella F, Pellicer A, Simón C.
Fertil Steril. 2013 Sep;100(3):818-24. doi: 10.1016/j.fertnstert.2013.05.004. Epub 2013 Jun 4.
PMID:23756099
Ruiz-Alonso M, Galindo N, Pellicer A, Simón C.
Hum Reprod. 2014 Jun;29(6):1244-7. doi: 10.1093/humrep/deu070. Epub 2014 Apr 15.
PMID:24737781
Ruiz-Alonso M, Galindo N, Pellicer A, Simón C.
Hum Reprod. 2014 Jun;29(6):1244-7. doi: 10.1093/humrep/deu070. Epub 2014 Apr 15.
PMID:24737781
Nejat EJ, Ruiz-Alonso M, Simón C, Meier UT.
Fertil Steril. 2014 Nov;102(5):1477-81. doi: 10.1016/j.fertnstert.2014.07.1254. Epub 2014 Sep 17.
PMID25241377
Bermejo A, Cerrillo M, Ruiz-Alonso M, Blesa D, Simón C, Pellicer A, Garcia-Velasco JA.
Fertil Steril. 2014 Jan;101(1):138-146.e3. doi: 10.1016/j.fertnstert.2013.09.033. Epub 2013 Oct 29.
PMID:24182413
Is endometrial receptivity transcriptomics affected in women with endometriosis? A pilot study.
Garcia-Velasco JA, Fassbender A, Ruiz-Alonso M, Blesa D, D’Hooghe T, Simon C.
Reprod Biomed Online. 2015 Nov;31(5):647-54. doi: 10.1016/j.rbmo.2015.07.014. Epub 2015 Aug 11.
PMID:26385059
Strug MR, Su R, Young JE, Dodds WG, Shavell VI, Díaz-Gimeno P, Ruíz-Alonso M, Simón C, Lessey BA, Leach RE, Fazleabas AT.
Hum Reprod. 2016 Jul;31(7):1552-61. doi: 10.1093/humrep/dew080. Epub 2016 Apr 26.
PMID:27122490
Comstock IA, Diaz-Gimeno P, Cabanillas S, Bellver J, Sebastian-Leon P, Shah M, Schutt A, Valdes CT, Ruiz-Alonso M, Valbuena D, Simon C, Lathi RB.
Fertil Steril. 2017 Mar;107(3):740-748.e2. doi: 10.1016/j.fertnstert.2016.11.009. Epub 2016 Dec 2.
PMID:27919438
Díaz-Gimeno P, Ruiz-Alonso M, Sebastian-Leon P, Pellicer A, Valbuena D, Simón C.
Fertil Steril. 2017 Oct;108(4):703-710.e3. doi: 10.1016/j.fertnstert.2017.07.007. Epub 2017 Aug 30.
PMID:28863933
Inter-cycle consistency versus test compliance in endometrial receptivity analysis test.
Stankewicz T, Valbuena D, Ruiz-Alonso M.
J Assist Reprod Genet. 2018 May 26. doi: 10.1007/s10815-018-1212-7
Effect of mifepristone on the transcriptomic signature of endometrial receptivity.
von Grothusen C, Lalitkumar PG, Ruiz-Alonso M, Boggavarapu NR, Navarro R, Miravet-Valenciano J, Gemzell-Danielsson K, Simon C.
Hum Reprod. 2018 Aug 22. doi: 10.1093/humrep/dey272. [Epub ahead of print] PMID: 30137464
Live birth after embryo transfer in an unresponsive thin endometrium.
Gynecol Endocrinol. 2014 Jul;30(7):481-4. doi: 10.3109/09513590.2014.900747. Epub 2014 Mar 20.
Endometrial receptivity array: Clinical application.
Mahajan N.
J Hum Reprod Sci. 2015 Jul-Sep;8(3):121-9. doi: 10.4103/0974-1208.165153. Review.
PMID:26538853
Hashimoto T, Koizumi M, Doshida M, Toya M, Sagara E, Oka N, Nakajo Y, Aono N, Igarashi H, Kyono K.
Reprod Med Biol. 2017 Jun 27;16(3):290-296. doi: 10.1002/rmb2.12041. eCollection 2017 Jul.
PMID:29259480
Tan J, Kan A, Hitkari J, Taylor B, Tallon N, Warraich G, Yuzpe A, Nakhuda G.
J Assist Reprod Genet. 2018 Jan 11. doi: 10.1007/s10815-017-1112-2.
PMID:29327111
The Reproductive Outcomes for the Infertile Patients with Recurrent Implantation Failures May Be Improved by Endometrial Receptivity Array Test.
Ota, T., Funabiki, M., Tada, Y., Karita, M., Hayashi, T., Maeda, K. et al.
Journal of Medical Cases. 2019; 10(5), 138-140. doi: https://doi.org/10.14740/jmc3282
Why results of endometrial receptivity assay testing should not be discounted in recurrent implantation failure?
Simrandeep K., Padmaja N. The Onco Fertility Journal. 2019; 2(1): 46-49.
Personalized Embryo Transfer Helps in Improving In vitro Fertilization/ICSI Outcomes in Patients with Recurrent Implantation Failure.
Patel JA, Patel AJ, Banker JM, Shah SI, Banker MR. J Hum Reprod Sci. 2019; 12(1):59-66. doi: 10.4103/jhrs.JHRS_74_18.
Endometrial Receptivity Analysis – a tool to increase an implantation rate in assisted reproduction.
Hromadová L; Tokareva I; Veselá K; Trávník P; Veselý J. Ceska Gynekol. 2019; 84(3): 177-183.
Barrenetxea G, Romero I, Celis R, Abio A, Bilbao M, Barrenetxea J. Eur J Obstet Gynecol Reprod Biol. 2021 Aug;263:192-197.
